Helix GenoSphere
Claude connectorQuery human genomics & longitudinal clinical data
Bring Helix GenoSphere™ — a growing research clinico-genomic dataset of more than 500,000 exome-sequenced participants with linked longitudinal EHR data — directly into Claude. Query gene-level carrier counts and pathogenic variants, determine target genes on curated panels, search standardized medical vocabularies (conditions, drugs, labs), and obtain privacy-protected patient counts for any concept. All responses are aggregated and statistically de-identified, with small groups suppressed to protect participant privacy. A read-only window into population-scale genomics, no SQL required.
- Tools
- 5
exposed by this connector
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In its category
How this connector compares with others in the same category. Positions are counted within the category, not across the whole directory.
Life sciences16th of 18 by popularity · not ranked by trending score
| # | Connector | Popularity | Trending | 7d |
|---|---|---|---|---|
| 14 | 15,279 | 3,217 #15 | 4places down | |
| 15 | 15,005 | 5,633 #14 | 6places down | |
| 16 | 14,962 | — | 5places down | |
| 17 | 14,947 | 16,246 #9 | 0 | |
| 18 | 9,243 | — | 2,289places up |
This connector isn’t ranked by trending score, so the category’s top connectors are shown instead.
| # | Connector | Trending | Popularity | 7d |
|---|---|---|---|---|
| 1 |  PubMed | 49,454 | 19,228 #1 | 53places down |
| 2 |  Clinical Trials | 33,010 | 18,238 #2 | 1,665places up |
| 3 | 29,784 | 17,012 #5 | 147places down | |
| 4 |  bioRxiv | 29,294 | 17,999 #3 | 1,421places up |
| 5 | 27,782 | 16,726 #7 | 127places down |
Install
claude mcp add --transport http helix-genosphere https://mcp.hrn-production.helix.com/mcp
Tools
- get_variant_frequency
- check_gene_availability
- get_dataset_overview
- search_concepts
- get_patient_count
- Categories
- Sign-in
- Required
- Connector URL
- https://mcp.hrn-production.helix.com/mcp
- Transport
- Streamable HTTP
- Permissions
- Read
- Works with
- Claude, Claude Desktop, Claude API
- Acts on
- Reference docs
- Industry
- Health & life sciences
- Added
- June 19, 2026
- More info
- Sponsorship
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